Verne (Clark Gable) wants nothing more than to escape from a penal colony located off the northern coast of South America. He tries to involve Julie (Joan Crawford), a saloon girl, in his plans but she turns him in to the authorities. On Verne's next try, he piggybacks on the escape of six other convicts and runs into Julie again in the process. One of the convicts is a spiritual figure (Ian Hunter) who seems to know what will happen before anyone else. The group attempts to travel through the jungle, board a boat, and make it to the mainland.